High flow oxygen6/7/2023 Its evolution is marked by iterative episodes of acute-on-chronic respiratory failure with hypercapnia. Cystic fibrosis also affects intestinal function, leading to pancreatic insufficiency and malnutrition that may alter muscular function and worsen respiratory failure. This protein dysfunction directly provokes thick mucus into bronchi promoting pulmonary infections and leading to development of chronic obstructive pulmonary disease (COPD), followed by chronic respiratory failure. The disease occurs most often from birth and affects mainly the lungs. Accepted for publication Nov 27, 2018.Ĭystic fibrosis is an autosomal recessive genetic disease that provokes dysfunction of the cystic fibrosis transmembrane conductance regulator (CFTR). High-flow nasal oxygen versus noninvasive ventilation in adult patients with cystic fibrosis: a randomized crossover physiological study. Email: This is an invited Editorial commissioned by Section Editor Guo-Wei Tu, MD, PhD (Department of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China).Ĭomment on: Sklar MC, Dres M, Rittayamai N, et al. Réanimation Médicale, CHU de Poitiers, 2 rue la Milétrie, 86021 Poitiers Cedex, France. Policy of Dealing with Allegations of Research MisconductĬorrespondence to: Arnaud W.Policy of Screening for Plagiarism Process.
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